Transient calcium-dependent potassium current in magnocellular neurosecretory cells of the rat supraoptic nucleus.
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منابع مشابه
Endogenous Activation of Supraoptic Nucleus -Opioid Receptors Terminates Spontaneous Phasic Bursts in Rat Magnocellular Neurosecretory Cells
Brown, Colin H., Gareth Leng, Mike Ludwig, and Charles W. Bourque. Endogenous activation of supraoptic nucleus -opioid receptors terminates spontaneous phasic bursts in rat magnocellular neurosecretory cells. J Neurophysiol 95: 3235–3244, 2006. First published February 22, 2006; doi:10.1152/jn.00062.2006. Phasic activity in magnocellular neurosecretory vasopressin cells is characterized by alte...
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Phasic activity in magnocellular neurosecretory vasopressin cells is characterized by alternating periods of activity (bursts) and silence. During phasic bursts, action potentials (spikes) are superimposed on plateau potentials that are generated by summation of depolarizing after-potentials (DAPs). Burst termination is believed to result from autocrine feedback inhibition of plateau potentials...
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BACKGROUND NaV1.7 is preferentially expressed, at relatively high levels, in peripheral neurons, and is often referred to as a "peripheral" sodium channel, and NaV1.7-specific blockers are under study as potential pain therapeutics which might be expected to have minimal CNS side effects. However, occasional reports of patients with NaV1.7 gain-of-function mutations and apparent hypothalamic dy...
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Oxytocin- and vasopressin-producing magnocellular neurons (MCNs) of the hypothalamo-neurohypophysial system are the only neuronal phenotypes present in the rat supraoptic nucleus (SON). Laser microdissection of the SON, extraction and T7-based amplification of its RNAs, and analysis of the resulting cDNAs by hybridization on a 35, 319 element DNA microarray have provided a detailed composite vi...
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KEY POINTS A growing body of evidence suggests that epithelial Na+ channels (ENaCs) in the brain play a significant role in the regulation of blood pressure; however, the brain structures that mediate the effect are not well understood. Because vasopressin (VP) neurons play a pivotal role in coordinating neuroendocrine and autonomic responses to maintain cardiovascular homeostasis, a basic unde...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1988
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1988.sp017004